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Dig Dis Sci
Chemical Name: N-(3-Chloro-1H-indol-7-yl)-1
FTY720 (10 nM) alone exerts no effect on the expression of co-stimulatory molecules
6-dihydroxyphenyl)-3-(3-hydroxy-4-methoxyphenyl)propan-1-one
Discovery of XL888: a novel tropane-derived small molecule inhibitor of HSP90
R-1479 Size:Solid 2 mg Dig Dis SciR 1479, also known as 4' azidocytidine, is a potent inhibitor of NS5B dependent RNA synthesis and hepatitis C virus replication in cell culture. R 1479 is a specific inhibitor of HCV replication in the HCV subgenomic replicon system (IC(50) = 1. 28 microM). The corresponding 5' triphosphate derivative (R1479 TP) is a potent inhibitor of native HCV replicase isolated from replicon cells and of recombinant HCV polymerase (NS5B) mediated RNA synthesis